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Feb 10, 2006 · We report here the x-ray structure of a covalent serpin-proteinase complex, alpha1-proteinase inhibitor (alpha1PI) with porcine pancreatic ...
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May 1, 1988 · An inhibitor-proteinase complex consisting of human alpha 1-PI and human leukocyte elastase is chemotactic for human neutrophils.
Cystatin C is a low-molecular-weight (13 000 Da) endogenous cysteine proteinase inhibitor that is synthesized at a relatively constant rate and released into ...
1) (9, 10, 11, 12, 13, 14, 15). This mechanism involves formation of an initial noncovalent Michaelis-like complex between the proteinase and specificity- ...
May 3, 2001 · We have used [1H-15N]-HSQC NMR to investigate the structural changes that occur in both serpin and proteinase in forming the kinetically ...
Jul 25, 2023 · now, I3C NMR spectroscopy studies have only been useful in examining complexes formed with either pep- tide-related or small protein ...
Feb 23, 1999 · This approach affords a fast turnaround of structural information for iterative rational drug designs and obviates the need for studying the ...
Aug 12, 2008 · Neutrophil elastase reduces secretion of secretory leukoproteinase inhibitor (SLPI) by lung epithelial cells: role of charge of the proteinase- ...
ARG80507 Human Neutrophil Elastase / alpha 1 Proteinase Inhibitor Complex ELISA Kit is an Enzyme Immunoassay kit for the quantification of Human Neutrophil ...
Abstract. α1-Proteinase inhibitor (α1-PI) is a member of the serpin superfamily of serine proteinase inhibitors that are involved in the regulation of a nu.